Drug Detail


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Drug Name Darolutamide
Trade Name Nubeqa
Synonyms BAY1841788|ODM-201
Drug Descriptions

Nubeqa (darolutamide) is an androgen receptor antagonist that binds to and prevents nuclear translocation of the androgen receptor, thereby inhibiting expression of genes downstream of androgen receptor signaling that regulate proliferation of prostate cancer cells (PMID: 28490267). Nubeqa (darolutamide) is FDA approved for use in patients with non-metastatic castration-resistant prostate cancer (FDA.gov).

DrugClasses Hormone - Anti-androgens 29
CAS Registry Number 1297538-32-9
NCIT ID C104748


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Darolutamide Avelumab Darolutamide 0 0
Darolutamide Darolutamide 1 12
Darolutamide + Degarelix Darolutamide Degarelix 0 1
Darolutamide + Docetaxel Darolutamide Docetaxel 0 1
Darolutamide + Goserelin Darolutamide Goserelin 0 1
Darolutamide + Leuprolide Darolutamide Leuprolide 0 1
Darolutamide + Radium Ra 223 dichloride Darolutamide Radium Ra 223 dichloride 0 1
Darolutamide + Triptorelin Darolutamide Triptorelin 0 1

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