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Drug Name Relugolix
Trade Name
Synonyms TAK-385|Relumina
Drug Descriptions

Relugolix (TAK-385) is a gonadotropin-releasing hormone antagonist, which binds to the gonadotropin-releasing hormone receptor, thereby preventing the secretion and release of luteinizing hormone and follicle stimulating hormone and possibly resulting in anti-tumor activity (PMID: 32469183).

DrugClasses
CAS Registry Number 737789-87-6
NCIT ID C114498

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Prednisone + Relugolix Abiraterone Prednisone Relugolix 0 1
Abiraterone + Relugolix Abiraterone Relugolix 0 1
Darolutamide + Relugolix Darolutamide Relugolix 0 1
Docetaxel + Relugolix Docetaxel Relugolix 0 1
Enzalutamide + Relugolix Enzalutamide Relugolix 0 2
Estradiol + Norethindrone + Relugolix Estradiol Norethindrone Relugolix 0 0
Itraconazole + Relugolix Itraconazole Relugolix 0 1
Relugolix Relugolix 0 7
Relugolix + Ritonavir Relugolix Ritonavir 0 1


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