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| Drug Name | Azacitidine |
| Trade Name | Vidaza |
| Synonyms | azacytidine|CC-486|5-azacytidine|5-AC|U-18496|Onureg |
| Drug Descriptions |
Vidaza (azacitidine) is a cytidine analog that incorporates into DNA and RNA and binds to DNA methyltransferases (DNMTs), resulting in DNMT degradation and decreased DNA methylation, and leading to increased tumor cell death (PMID: 28159832, PMID: 28067760). Vidaza (azacitidine) is FDA-approved for use in patients with some subtypes of myelodysplastic syndrome and Onureg (azacitidine) is FDA approved for use in continued treatment of acute myeloid leukemia(FDA.gov). |
| DrugClasses | DNMT inhibitor (Pan) 5 |
| CAS Registry Number | 320-67-2 |
| NCIT ID | C288 |
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