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| Drug Name | Nintedanib |
| Trade Name | Ofev |
| Synonyms | BIBF 1120|Vargatef|BIBF 1120 |
| Drug Descriptions |
Ofev (nintedanib) is a triple angiokinase inhibitor that acts by blocking VEGFR, FGFR, RET, and PDGFR, thereby preventing tumorigenesis (PMID: 24947258, PMID: 24561444). Ofev (nintedanib) is FDA approved for use in patients with idiopathic pulmonary fibrosis (FDA.gov). |
| DrugClasses | FGFR Inhibitor (Pan) 25 PDGFR Inhibitor (Pan) 28 RET Inhibitor 50 VEGFR Inhibitor (Pan) 35 |
| CAS Registry Number | 656247-17-5 |
| NCIT ID | C62765 |
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