Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Canakinumab
Trade Name Ilaris
Synonyms ACZ-885
Drug Descriptions

Ilaris (canakinumab) is a monoclonal antibody against interleukin-1beta, which has anti-inflammatory activity and may decrease tumor progression (PMID: 28855077).

CAS Registry Number 914613-48-2
NCIT ID C80971


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Canakinumab Azacitidine Canakinumab 0 1
Canakinumab Canakinumab 0 5
Canakinumab + Carboplatin + Spartalizumab Canakinumab Carboplatin Spartalizumab 0 1
Canakinumab + Cisplatin + Pemetrexed Disodium + Spartalizumab Canakinumab Cisplatin Pemetrexed Disodium Spartalizumab 0 1
Canakinumab + Darbepoetin Alfa Canakinumab Darbepoetin Alfa 0 1
Canakinumab + Docetaxel Canakinumab Docetaxel 0 1
Canakinumab + Durvalumab Canakinumab Durvalumab 0 1
Canakinumab + Gemcitabine + Nab-paclitaxel + Spartalizumab Canakinumab Gemcitabine Nab-paclitaxel Spartalizumab 0 1
Canakinumab + Ieramilimab + Spartalizumab Canakinumab Ieramilimab Spartalizumab 0 1
Canakinumab + Pembrolizumab Canakinumab Pembrolizumab 0 2
Canakinumab + Sabatolimab Canakinumab Sabatolimab 0 1
Canakinumab + Spartalizumab Canakinumab Spartalizumab 0 3

Additional content available in CKB BOOST