Drug Detail

Drug Name Spartalizumab
Trade Name
Synonyms PDR001
Drug Descriptions

Spartalizumab (PDR001) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 99 PD-L1/PD-1 antibody 50

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BLZ945 + Spartalizumab BLZ945 Spartalizumab 0 1
Canakinumab + Spartalizumab Canakinumab Spartalizumab 0 2
Capmatinib + Spartalizumab Capmatinib Spartalizumab 0 3
Carboplatin + Cisplatin + Pemetrexed + Spartalizumab Carboplatin Cisplatin Pemetrexed Spartalizumab 0 1
Carboplatin + LAG525 + Spartalizumab Carboplatin LAG525 Spartalizumab 0 1
Carboplatin + Paclitaxel + Spartalizumab Carboplatin Paclitaxel Spartalizumab 0 1
Cisplatin + Gemcitabine + Spartalizumab Cisplatin Gemcitabine Spartalizumab 0 1
Cisplatin + Pemetrexed + Spartalizumab Cisplatin Pemetrexed Spartalizumab 0 1
CJM112 + Spartalizumab CJM112 Spartalizumab 0 2
Dabrafenib + Spartalizumab + Trametinib Dabrafenib Spartalizumab Trametinib 0 2
Decitabine + MBG453 + Spartalizumab Decitabine MBG453 Spartalizumab 0 1
Decitabine + Spartalizumab Decitabine Spartalizumab 0 1
Everolimus + Spartalizumab Everolimus Spartalizumab 0 1
FAZ053 + Spartalizumab FAZ053 Spartalizumab 0 1
Fulvestrant + Ribociclib + Spartalizumab Fulvestrant Ribociclib Spartalizumab 0 1
GWN 323 + Spartalizumab GWN 323 Spartalizumab 0 1
LAG525 + Spartalizumab LAG525 Spartalizumab 0 2
LCL161 + Spartalizumab LCL161 Spartalizumab 0 2
LGK974 + Spartalizumab LGK974 Spartalizumab 0 1
LHC165 + Spartalizumab LHC165 Spartalizumab 0 1
LXH 254 + Spartalizumab LXH 254 Spartalizumab 0 1
MBG453 + Spartalizumab MBG453 Spartalizumab 7 1
MCS110 + Spartalizumab MCS110 Spartalizumab 0 1
MIW815 + Spartalizumab MIW815 Spartalizumab 2 1
Nazartinib + Spartalizumab Nazartinib Spartalizumab 0 1
NIS793 + Spartalizumab NIS793 Spartalizumab 0 1
NIZ985 + Spartalizumab NIZ985 Spartalizumab 0 1
NZV930 + PBF-509 + Spartalizumab NZV930 PBF-509 Spartalizumab 0 1
NZV930 + Spartalizumab NZV930 Spartalizumab 0 1
Panobinostat + Spartalizumab Panobinostat Spartalizumab 0 1
PBF-509 + Spartalizumab PBF-509 Spartalizumab 0 2
Regorafenib + Spartalizumab Regorafenib Spartalizumab 0 1
Ribociclib + Spartalizumab Ribociclib Spartalizumab 0 1
Sorafenib + Spartalizumab Sorafenib Spartalizumab 0 1
Spartalizumab Spartalizumab 0 8
Spartalizumab + Trametinib Spartalizumab Trametinib 0 1