Drug Detail


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Drug Name MCS110
Trade Name
Synonyms Lacnotuzumab
Drug Descriptions

Lacnotuzumab (MCS110) is a monoclonal antibody that binds CSF1 and prevents receptor binding and subsequent receptor activation, and leads to reduction of tumor-related bone destruction (Cancer Res; 2009 Apr 18-22; Abstract nr DDT02-2).

DrugClasses CSF1 Antibody 2
CAS Registry Number 1831128-32-5
NCIT ID C80044


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + Doxorubicin + MCS110 + Paclitaxel Cyclophosphamide Doxorubicin MCS110 Paclitaxel 0 1
Dabrafenib + MCS110 + Trametinib Dabrafenib MCS110 Trametinib 0 1
Ieramilimab + MCS110 + Spartalizumab Ieramilimab MCS110 Spartalizumab 0 1
MCS110 MCS110 0 2
MCS110 + Spartalizumab MCS110 Spartalizumab 0 1

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