Drug Detail

Drug Name PBF-509
Trade Name
Synonyms NIR178
Drug Descriptions

PBF-509 binds to and inhibits the adenosine A2A (ADORA2A) receptor on immune cells, resulting in activation of an anti-tumor immune response by blocking binding of the immunosuppressive metabolite, adenosine (PMID: 29758241, PMID: 28582704).

DrugClasses Immune Checkpoint Inhibitor 99

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