Drug Detail


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Drug Name SL-172154
Trade Name
Synonyms SL172154|SL 172154|CD172a-Fc-CD40L Chimeric Protein SL-172154
Drug Descriptions

SL-172154 is a fusion protein that is engineered to target CD47 on tumor cells and CD40 on antigen presenting cells (APCs), which inhibits CD47/SIRPa signaling and potentially results in increased anti-tumor immune response (NCI Drug Dictionary).

CAS Registry Number NA
NCIT ID C173706


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + SL-172154 Azacitidine SL-172154 0 1
Azacitidine + SL-172154 + Venetoclax Azacitidine SL-172154 Venetoclax 0 1
Mirvetuximab Soravtansine + SL-172154 Mirvetuximab Soravtansine SL-172154 0 1
Pegylated liposomal doxorubicin + SL-172154 Pegylated liposomal doxorubicin SL-172154 0 1
SL-172154 SL-172154 0 3
SL-172154 + Venetoclax SL-172154 Venetoclax 0 0

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