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| Drug Name | Glasdegib |
| Trade Name | Daurismo |
| Synonyms | PF-04449913 |
| Drug Descriptions |
Daurismo (glasdegib) inhibits Smoothened (SMO), resulting in decreased Hedgehog (Hh) pathway signalling, and potentially inhibiting Hh-mediated tumor growth (PMID: 24900436, PMID: 25388167). Daurismo (glasdegib) is FDA approved for use in combination with low-dose cytarabine in patients 75 years old or older with newly-diagnosed acute myeloid leukemia (FDA.gov). |
| DrugClasses | SMO Inhibitor 16 |
| CAS Registry Number | 1095173-27-5 |
| NCIT ID | C84862 |
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