Drug Detail


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Drug Name Uproleselan
Trade Name
Synonyms GMI-1271
Drug Descriptions

Uproleselan (GMI-1271) is a small molecule that binds to E-selectin and prevents E-selectin mediated cell-cell interaction, therefore, modulating inflammation and tumor progression (PMID: 26834953).

CAS Registry Number 1983970-12-2
NCIT ID C119743


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Uproleselan + Venetoclax Azacitidine Uproleselan Venetoclax 0 1
Cladribine + Cytarabine + Uproleselan Cladribine Cytarabine Uproleselan 0 1
Cytarabine + Daunorubicin + Uproleselan Cytarabine Daunorubicin Uproleselan 0 1
Cytarabine + Etoposide + Mitoxantrone + Uproleselan Cytarabine Etoposide Mitoxantrone Uproleselan 0 1
Cytarabine + Fludarabine + Idarubicin + Uproleselan Cytarabine Fludarabine Idarubicin Uproleselan 0 1
Cytarabine + Fludarabine + Uproleselan Cytarabine Fludarabine Uproleselan 0 1
Cytarabine + Uproleselan Cytarabine Uproleselan 0 1
Gemcitabine + Uproleselan Gemcitabine Uproleselan 0 0
Uproleselan Uproleselan 0 1

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