Drug Detail


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Drug Name CB-839
Trade Name
Drug Descriptions

CB-839 binds to and inhibits glutaminase, preventing the conversion of glutamine to glutamate, which results in a decrease in cell proliferation (NCI Drug Dictionary).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARQ761 + CB-839 ARQ761 CB-839 0 0
Azacitidine + CB-839 Azacitidine CB-839 0 1
Cabozantinib + CB-839 CB-839 Cabozantinib 0 2
Capecitabine + CB-839 CB-839 Capecitabine 0 1
CB-839 CB-839 1 3
CB-839 + Docetaxel CB-839 Docetaxel 0 1
CB-839 + Erlotinib CB-839 Erlotinib 0 1
CB-839 + Everolimus CB-839 Everolimus 1 2
CB-839 + Irinotecan + Panitumumab CB-839 Irinotecan Panitumumab 0 1
CB-839 + Niraparib CB-839 Niraparib 0 1
CB-839 + Nivolumab CB-839 Nivolumab 0 1
CB-839 + Olaparib CB-839 Olaparib 1 0
CB-839 + Osimertinib CB-839 Osimertinib 0 1
CB-839 + Paclitaxel CB-839 Paclitaxel 0 1
CB-839 + Palbociclib CB-839 Palbociclib 0 1
CB-839 + Radiotherapy + Temozolomide CB-839 Radiotherapy Temozolomide 0 1
CB-839 + Talazoparib CB-839 Talazoparib 0 1

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