Drug Detail

Drug Name Panitumumab
Trade Name Vectibix
Synonyms ABX-EGF
Drug Descriptions

Vectibix (panitumumab) is a monoclonal antibody directed against EGFR, which inhibits cell proliferation and induces apoptosis (PMID: 18998757). Vectibix (panitumumab) is FDA approved for metastatic colorectal cancer patients with wild-type KRAS and NRAS (FDA.gov).

DrugClasses EGFR Antibody 27

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Binimetinib + Encorafenib + Panitumumab Binimetinib Encorafenib Panitumumab 2 0
Binimetinib + Panitumumab Binimetinib Panitumumab 1 0
Buparlisib + Panitumumab Buparlisib Panitumumab 0 1
Cabozantinib + Panitumumab Cabozantinib Panitumumab 0 1
Capecitabine + Panitumumab Capecitabine Panitumumab 0 1
Carboplatin + Gemcitabine + Panitumumab Carboplatin Gemcitabine Panitumumab 0 1
Carboplatin + Nab-paclitaxel + Panitumumab Carboplatin Nab-paclitaxel Panitumumab 0 1
Carboplatin + Paclitaxel + Panitumumab Carboplatin Paclitaxel Panitumumab 0 2
CB-839 + Irinotecan + Panitumumab CB-839 Irinotecan Panitumumab 0 1
Dabrafenib + Panitumumab Dabrafenib Panitumumab 2 1
Dabrafenib + Panitumumab + Trametinib Dabrafenib Panitumumab Trametinib 4 1
Dexamethasone + Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Panitumumab Dexamethasone Floxuridine Fluorouracil Irinotecan Leucovorin Panitumumab 0 1
Erlotinib + Panitumumab Erlotinib Panitumumab 0 1
Everolimus + Ganitumab + Panitumumab Everolimus Ganitumab Panitumumab 0 1
Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Floxuridine Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 0
Fluorouracil + Irinotecan + Leucovorin + Panitumumab Fluorouracil Irinotecan Leucovorin Panitumumab 0 0
Fluorouracil + Irinotecan + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Oxaliplatin Panitumumab 0 0
Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Leucovorin Oxaliplatin Panitumumab 0 2
Fluorouracil + Leucovorin + Panitumumab Fluorouracil Leucovorin Panitumumab 0 1
Fluorouracil + Oxaliplatin + Panitumumab Fluorouracil Oxaliplatin Panitumumab 0 0
Gemcitabine + Oxaliplatin + Panitumumab Gemcitabine Oxaliplatin Panitumumab 0 0
Ipilimumab + Nivolumab + Panitumumab Ipilimumab Nivolumab Panitumumab 0 1
Irinotecan + Panitumumab Irinotecan Panitumumab 1 0
Irinotecan + Panitumumab + Vemurafenib Irinotecan Panitumumab Vemurafenib 2 0
JNJ 38877605 + Panitumumab JNJ 38877605 Panitumumab 1 0
Napabucasin + Panitumumab Napabucasin Panitumumab 0 1
Niraparib + Panitumumab Niraparib Panitumumab 0 1
Paclitaxel + Panitumumab Paclitaxel Panitumumab 0 0
Panitumumab Panitumumab 40 16
Panitumumab + Regorafenib Panitumumab Regorafenib 0 1
Panitumumab + Rilotumumab Panitumumab Rilotumumab 0 0
Panitumumab + Trametinib Panitumumab Trametinib 3 2
Panitumumab + Vemurafenib Panitumumab Vemurafenib 8 0


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