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Drug Name Panitumumab
Trade Name Vectibix
Synonyms ABX-EGF
Drug Descriptions

Vectibix (panitumumab) is a monoclonal antibody directed against EGFR, which inhibits cell proliferation and induces apoptosis (PMID: 18998757). Vectibix (panitumumab) is FDA approved for metastatic colorectal cancer patients with wild-type KRAS and NRAS (FDA.gov).

DrugClasses EGFR Antibody 57
CAS Registry Number 339177-26-3
NCIT ID C1857

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Adagrasib + Panitumumab Adagrasib Panitumumab 0 0
Afatinib + Panitumumab Afatinib Panitumumab 0 0
Balstilimab + Botensilimab + Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Balstilimab Botensilimab Fluorouracil Leucovorin Oxaliplatin Panitumumab 0 1
Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Bevacizumab Fluorouracil Leucovorin Oxaliplatin Panitumumab 0 1
BGB3245 + Panitumumab BGB3245 Panitumumab 0 1
BI-4020 + Panitumumab BI-4020 Panitumumab 0 0
Binimetinib + Encorafenib + Panitumumab Binimetinib Encorafenib Panitumumab 0 0
Binimetinib + Panitumumab Binimetinib Panitumumab 1 0
BLU-945 + Panitumumab BLU-945 Panitumumab 0 0
Brigatinib + Panitumumab Brigatinib Panitumumab 0 0
Buparlisib + Panitumumab Buparlisib Panitumumab 0 1
Cabozantinib + Panitumumab Cabozantinib Panitumumab 0 1
Capecitabine + Oxaliplatin + Panitumumab Capecitabine Oxaliplatin Panitumumab 0 0
Capecitabine + Panitumumab Capecitabine Panitumumab 0 1
Carboplatin + Cyclophosphamide + Doxorubicin + Paclitaxel + Panitumumab + Pembrolizumab Carboplatin Cyclophosphamide Doxorubicin Paclitaxel Panitumumab Pembrolizumab 0 1
Carboplatin + Gemcitabine + Panitumumab Carboplatin Gemcitabine Panitumumab 0 1
Carboplatin + Nab-paclitaxel + Panitumumab Carboplatin Nab-paclitaxel Panitumumab 0 1
Carboplatin + Paclitaxel + Panitumumab Carboplatin Paclitaxel Panitumumab 0 2
Celecoxib + Dabrafenib + Panitumumab + Trametinib Celecoxib Dabrafenib Panitumumab Trametinib 1 0
Celecoxib + Encorafenib + Panitumumab Celecoxib Encorafenib Panitumumab 1 0
CEND-1 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab CEND-1 Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
Cetuximab + Divalproex sodium + Panitumumab Cetuximab Divalproex sodium Panitumumab 0 0
Cetuximab + Panitumumab Cetuximab Panitumumab 0 1
Cetuximab + Panitumumab + Valproic acid Cetuximab Panitumumab Valproic acid 0 1
Dabrafenib + Panitumumab Dabrafenib Panitumumab 2 1
Dabrafenib + Panitumumab + Trametinib Dabrafenib Panitumumab Trametinib 2 1
Dexamethasone + Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Panitumumab Dexamethasone Floxuridine Fluorouracil Irinotecan Leucovorin Panitumumab 0 1
Encorafenib + Hydroxychloroquine + Panitumumab Encorafenib Hydroxychloroquine Panitumumab 0 1
Encorafenib + Panitumumab Encorafenib Panitumumab 3 0
Erlotinib + Panitumumab Erlotinib Panitumumab 0 1
Everolimus + Ganitumab + Panitumumab Everolimus Ganitumab Panitumumab 0 1
Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Floxuridine Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
Fluorouracil + Irinotecan + Leucovorin + Panitumumab Fluorouracil Irinotecan Leucovorin Panitumumab 3 5
Fluorouracil + Irinotecan + Leucovorin + Panitumumab + SM08502 Fluorouracil Irinotecan Leucovorin Panitumumab SM08502 0 1
Fluorouracil + Irinotecan + Leucovorin + Panitumumab + Sotorasib Fluorouracil Irinotecan Leucovorin Panitumumab Sotorasib 0 0
Fluorouracil + Irinotecan + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Oxaliplatin Panitumumab 0 0
Fluorouracil + Irinotecan + Panitumumab + Sotorasib Fluorouracil Irinotecan Panitumumab Sotorasib 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Leucovorin Oxaliplatin Panitumumab 5 5
Fluorouracil + Leucovorin + Panitumumab Fluorouracil Leucovorin Panitumumab 0 1
Fluorouracil + Oxaliplatin + Panitumumab Fluorouracil Oxaliplatin Panitumumab 0 0
Gefitinib + Panitumumab Gefitinib Panitumumab 0 0
Gemcitabine + Oxaliplatin + Panitumumab Gemcitabine Oxaliplatin Panitumumab 0 0
Ipilimumab + Nivolumab + Panitumumab Ipilimumab Nivolumab Panitumumab 0 1
Irinotecan + Panitumumab Irinotecan Panitumumab 6 3
Irinotecan + Panitumumab + Telaglenastat Irinotecan Panitumumab Telaglenastat 0 1
Irinotecan + Panitumumab + Vemurafenib Irinotecan Panitumumab Vemurafenib 0 0
Iruplinalkib + Panitumumab Iruplinalkib Panitumumab 0 0
JNJ 38877605 + Panitumumab JNJ 38877605 Panitumumab 0 0
Napabucasin + Panitumumab Napabucasin Panitumumab 0 1
Niraparib + Panitumumab Niraparib Panitumumab 0 1
Osimertinib + Panitumumab Osimertinib Panitumumab 0 0
Paclitaxel + Panitumumab Paclitaxel Panitumumab 0 0
Paclitaxel + Panitumumab + Pembrolizumab Paclitaxel Panitumumab Pembrolizumab 0 0
Panitumumab Panitumumab 30 24
Panitumumab + Regorafenib Panitumumab Regorafenib 0 1
Panitumumab + Rilotumumab Panitumumab Rilotumumab 0 0
Panitumumab + RO5126766 Panitumumab RO5126766 0 0
Panitumumab + Sotorasib Panitumumab Sotorasib 2 3
Panitumumab + Sotorasib + Trametinib Panitumumab Sotorasib Trametinib 0 1
Panitumumab + Talimogene laherparepvec Panitumumab Talimogene laherparepvec 0 1
Panitumumab + Trametinib Panitumumab Trametinib 3 3
Panitumumab + Trifluridine-tipiracil hydrochloride Panitumumab Trifluridine-tipiracil hydrochloride 0 1
Panitumumab + Vemurafenib Panitumumab Vemurafenib 5 0


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