Drug Detail


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Drug Name Balstilimab
Trade Name
Synonyms AGEN-2034|AGEN2034
Drug Descriptions

Balstilimab (AGEN2034) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 ligand (CD274), potentially resulting in enhanced anti-tumor immune response (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3086-3086).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 96
CAS Registry Number 2230167-06-1
NCIT ID C136465


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AGEN1181 + AGEN1571 + Balstilimab AGEN1181 AGEN1571 Balstilimab 0 1
AGEN1181 + Balstilimab AGEN1181 Balstilimab 0 2
AGEN1181 + Balstilimab + Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin AGEN1181 Balstilimab Bevacizumab Fluorouracil Leucovorin Oxaliplatin 0 1
AGEN1571 + Balstilimab AGEN1571 Balstilimab 0 1
Balstilimab Balstilimab 0 5
Balstilimab + Cisplatin + Gemcitabine + Zalifrelimab Balstilimab Cisplatin Gemcitabine Zalifrelimab 0 1
Balstilimab + CR6086 Balstilimab CR6086 0 1
Balstilimab + Doxorubicin + Zalifrelimab Balstilimab Doxorubicin Zalifrelimab 0 1
Balstilimab + rHSC-DIPGVax Balstilimab rHSC-DIPGVax 0 1
Balstilimab + rHSC-DIPGVax + Zalifrelimab Balstilimab Zalifrelimab rHSC-DIPGVax 0 1
Balstilimab + Zalifrelimab Balstilimab Zalifrelimab 0 3

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