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Drug Name Balstilimab
Trade Name
Synonyms AGEN-2034|AGEN2034
Drug Descriptions

Balstilimab (AGEN2034) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 ligand (CD274), potentially resulting in enhanced anti-tumor immune response (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3086-3086).

DrugClasses Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117
CAS Registry Number 2230167-06-1
NCIT ID C136465

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AGEN1571 + Balstilimab AGEN1571 Balstilimab 0 1
AGEN1571 + Balstilimab + Botensilimab AGEN1571 Balstilimab Botensilimab 0 1
AgenT-797 + Balstilimab + Botensilimab + Paclitaxel + Ramucirumab AgenT-797 Balstilimab Botensilimab Paclitaxel Ramucirumab 0 1
Balstilimab Balstilimab 0 6
Balstilimab + Bevacizumab + Botensilimab + Fluorouracil + Leucovorin + Oxaliplatin Balstilimab Bevacizumab Botensilimab Fluorouracil Leucovorin Oxaliplatin 0 2
Balstilimab + Botensilimab Balstilimab Botensilimab 0 8
Balstilimab + Botensilimab + Celecoxib + Chloroquine phosphate + Cisplatin + Gemcitabine + Nab-paclitaxel Balstilimab Botensilimab Celecoxib Chloroquine phosphate Cisplatin Gemcitabine Nab-paclitaxel 0 1
Balstilimab + Botensilimab + Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Balstilimab Botensilimab Fluorouracil Leucovorin Oxaliplatin Panitumumab 0 1
Balstilimab + Botensilimab + GS-1423 Balstilimab Botensilimab GS-1423 0 1
Balstilimab + Botensilimab + Poly ICLC + Pooled Mutant KRAS-Targeted Long Peptide Vaccine Balstilimab Botensilimab Poly ICLC Pooled Mutant KRAS-Targeted Long Peptide Vaccine 0 0
Balstilimab + Botensilimab + Regorafenib Balstilimab Botensilimab Regorafenib 0 1
Balstilimab + Botensilimab + Vitamin C Balstilimab Botensilimab Vitamin C 0 1
Balstilimab + Cisplatin + Gemcitabine + Zalifrelimab Balstilimab Cisplatin Gemcitabine Zalifrelimab 0 1
Balstilimab + CR6086 Balstilimab CR6086 0 1
Balstilimab + Doxorubicin + Zalifrelimab Balstilimab Doxorubicin Zalifrelimab 0 1
Balstilimab + Gemcitabine + GS-1423 + Nab-paclitaxel Balstilimab GS-1423 Gemcitabine Nab-paclitaxel 0 1
Balstilimab + GS-1423 Balstilimab GS-1423 0 1
Balstilimab + MEN1309 Balstilimab MEN1309 0 1
Balstilimab + QS21 + TG01 Balstilimab QS21 TG01 0 1
Balstilimab + rHSC-DIPGVax Balstilimab rHSC-DIPGVax 0 1
Balstilimab + rHSC-DIPGVax + Zalifrelimab Balstilimab Zalifrelimab rHSC-DIPGVax 0 1
Balstilimab + Zalifrelimab Balstilimab Zalifrelimab 0 3


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