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Therapy Name AGEN1181 + Balstilimab
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
AGEN1181 AGEN 1181|AGEN-1181|Botensilimab CTLA4 Antibody 24 Immune Checkpoint Inhibitor 153 AGEN1181 is an antibody that targets CTLA4, potentially resulting in increased anti-tumor immune response (NCI Drug Dictionary).
Balstilimab AGEN-2034|AGEN2034 Immune Checkpoint Inhibitor 153 PD-L1/PD-1 antibody 100 Balstilimab (AGEN2034) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 ligand (CD274), potentially resulting in enhanced anti-tumor immune response (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3086-3086).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05571293 Phase II AGEN1181 + Balstilimab Combination Immunotherapy in Colorectal Cancer (NEST-1) Not yet recruiting USA 0
NCT05608044 Phase II AGEN1181 + Balstilimab AGEN1181 A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer Recruiting USA | ITA | FRA | ESP | BEL 0


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