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Drug Name Talimogene laherparepvec
Trade Name Imlygic
Synonyms OncoVEX GM-CSF
Drug Descriptions

Imlygic (talimogene laherparepvec) is a GM-CSF expressing herpes simplex type-1 virus (HSV-1) that selectively infects and lyses tumor cells, and potentially induces a cytotoxic immune response against tumor cells (PMID: 25777572). Imlygic (talimogene laherparepvec) is FDA approved for use in patients with recurrent melanoma (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anastrozole + Talimogene laherparepvec Anastrozole Talimogene laherparepvec 0 1
Atezolizumab + Talimogene laherparepvec Atezolizumab Talimogene laherparepvec 0 1
Capecitabine + Fluorouracil + Oxaliplatin + Talimogene laherparepvec Capecitabine Fluorouracil Oxaliplatin Talimogene laherparepvec 0 1
Dabrafenib + Talimogene laherparepvec + Trametinib Dabrafenib Talimogene laherparepvec Trametinib 0 2
Exemestane + Talimogene laherparepvec Exemestane Talimogene laherparepvec 0 1
Fulvestrant + Talimogene laherparepvec Fulvestrant Talimogene laherparepvec 0 1
Ipilimumab + Nivolumab + Talimogene laherparepvec Ipilimumab Nivolumab Talimogene laherparepvec 0 1
Letrozole + Talimogene laherparepvec Letrozole Talimogene laherparepvec 0 1
Nivolumab + Talimogene laherparepvec Nivolumab Talimogene laherparepvec 0 2
Nivolumab + Talimogene laherparepvec + Trabectedin Nivolumab Talimogene laherparepvec Trabectedin 0 1
Paclitaxel + Talimogene laherparepvec Paclitaxel Talimogene laherparepvec 0 2
Panitumumab + Talimogene laherparepvec Panitumumab Talimogene laherparepvec 0 1
Pembrolizumab + Talimogene laherparepvec Pembrolizumab Talimogene laherparepvec 0 5
Talimogene laherparepvec Talimogene laherparepvec 1 10
Talimogene laherparepvec + Tamoxifen Talimogene laherparepvec Tamoxifen 0 1


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