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| Drug Name | Trabectedin |
| Trade Name | Yondelis |
| Synonyms | ET-743 |
| Drug Descriptions |
Yondelis (trabectedin) is a marine-derived alkaloid that binds to DNA and induces DNA strand breaks, leading to cell cycle arrest and cell death in tumor cells (PMID: 24755886). Yondelis (trabectedin) is FDA approved for metastatic liposarcoma or leiomyosarcoma who received prior anthracycline treatment (FDA.gov). |
| DrugClasses | Chemotherapy - Alkylating 18 |
| CAS Registry Number | 114899-77-3 |
| NCIT ID | C1691 |
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