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Drug Name Infigratinib
Trade Name
Synonyms BGJ398|BGJ-398|BGJ 398
Drug Descriptions

Infigratinib (BGJ398) is pan-FGFR inhibitor, which inhibits tumor angiogenesis and tumor cell proliferation (PMID: 31109923, PMID: 30101387).

DrugClasses FGFR Inhibitor (Pan) 18

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + Infigratinib Alpelisib Infigratinib 3 1
Binimetinib + Encorafenib + Infigratinib Binimetinib Encorafenib Infigratinib 0 1
Buparlisib + Infigratinib Buparlisib Infigratinib 1 0
Crizotinib + Infigratinib Crizotinib Infigratinib 0 0
EMD 1214063 + Infigratinib EMD 1214063 Infigratinib 0 0
Encorafenib + Infigratinib Encorafenib Infigratinib 0 1
Fluorouracil + Infigratinib Fluorouracil Infigratinib 0 0
Fluorouracil + Infigratinib + Irinotecan + Oxaliplatin Fluorouracil Infigratinib Irinotecan Oxaliplatin 0 1
Ganetespib + Infigratinib Ganetespib Infigratinib 1 0
Imatinib + Infigratinib Imatinib Infigratinib 3 1
Infigratinib Infigratinib 96 12
Infigratinib + Olaparib Infigratinib Olaparib 0 0
Infigratinib + Oxaliplatin Infigratinib Oxaliplatin 0 0
Infigratinib + Pictilisib Infigratinib Pictilisib 0 0
Infigratinib + Sapanisertib Infigratinib Sapanisertib 2 0
Infigratinib + Talazoparib Infigratinib Talazoparib 0 0
Infigratinib + Trabectedin Infigratinib Trabectedin 1 0
Infigratinib + Trametinib Infigratinib Trametinib 3 0


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