Drug Detail

Drug Name Dacarbazine
Trade Name Deticene
Synonyms Biocarbazine R
Drug Descriptions

Deticene (dacarbazine) alkylates and cross-links DNA, which disrupts the cell-cycle (NCI Drug Dictionary). Dacarbazine is FDA approved for melanoma (FDA.gov).

DrugClasses Chemotherapy - Alkylating 14

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bleomycin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Vinblastine Bleomycin Dacarbazine Doxorubicin Vinblastine 0 1
Brentuximab vedotin + Dacarbazine Brentuximab vedotin Dacarbazine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Vinblastine 1 1
Dacarbazine Dacarbazine 0 8
Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 2
Dacarbazine + PTC596 Dacarbazine PTC596 0 1
Dacarbazine + Ramucirumab Dacarbazine Ramucirumab 0 0
Dacarbazine + Selumetinib Dacarbazine Selumetinib 3 1


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