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Drug Name Ifosfamide
Trade Name Cyfos
Synonyms Z4942
Drug Descriptions

Cyfos (ifosfamide) is an alkylating agent, which cross-links DNA, thereby inhibiting DNA replication (NCI Drug Dictionary).

DrugClasses Chemotherapy - Alkylating 18
CAS Registry Number 3778-73-2
NCIT ID C564

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Carboplatin + Etoposide + Ifosfamide + Rituximab Acalabrutinib Carboplatin Etoposide Ifosfamide Rituximab 0 2
ADI-PEG 20 + Ifosfamide + Mesna ADI-PEG 20 Ifosfamide Mesna 0 1
Alectinib + Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Etoposide + Ifosfamide + Methotrexate + Vindesine Alectinib Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Ifosfamide Methotrexate Vindesine 0 0
Avelumab + Carboplatin + Etoposide + Ifosfamide + Rituximab + Utomilumab Avelumab Carboplatin Etoposide Ifosfamide Rituximab Utomilumab 0 1
Bevacizumab + Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Irinotecan + Sorafenib + Temozolomide + Temsirolimus + Vincristine Sulfate Bevacizumab Cyclophosphamide Doxorubicin Etoposide Ifosfamide Irinotecan Sorafenib Temozolomide Temsirolimus Vincristine Sulfate 0 1
Brentuximab vedotin + Carboplatin + Etoposide + Ifosfamide Brentuximab vedotin Carboplatin Etoposide Ifosfamide 0 1
Cabozantinib + Ifosfamide Cabozantinib Ifosfamide 0 1
Calaspargase pegol-mknl + Dexamethasone + Etoposide + Ifosfamide + Methotrexate Calaspargase pegol-mknl Dexamethasone Etoposide Ifosfamide Methotrexate 0 1
Carboplatin + Dexamethasone + Etoposide + Ifosfamide + Rituximab Carboplatin Dexamethasone Etoposide Ifosfamide Rituximab 0 1
Carboplatin + Dexamethasone + Idarubicin + Ifosfamide + Rituximab + Vincristine Sulfate Carboplatin Dexamethasone Idarubicin Ifosfamide Rituximab Vincristine Sulfate 0 1
Carboplatin + Etoposide + Glofitamab-gxbm + Ifosfamide + Obinutuzumab + Rituximab Carboplatin Etoposide Glofitamab-gxbm Ifosfamide Obinutuzumab Rituximab 0 1
Carboplatin + Etoposide + Glofitamab-gxbm + Ifosfamide + Obinutuzumab + Rituximab + Tocilizumab Carboplatin Etoposide Glofitamab-gxbm Ifosfamide Obinutuzumab Rituximab Tocilizumab 0 1
Carboplatin + Etoposide + Glofitamab-gxbm + Ifosfamide + Rituximab Carboplatin Etoposide Glofitamab-gxbm Ifosfamide Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide Carboplatin Etoposide Ifosfamide 0 7
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Rituximab Carboplatin Etoposide Ifosfamide Lenalidomide Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Tafasitamab-cxix Carboplatin Etoposide Ifosfamide Lenalidomide Tafasitamab-cxix 0 1
Carboplatin + Etoposide + Ifosfamide + Nivolumab Carboplatin Etoposide Ifosfamide Nivolumab 0 1
Carboplatin + Etoposide + Ifosfamide + Obinutuzumab Carboplatin Etoposide Ifosfamide Obinutuzumab 0 1
Carboplatin + Etoposide + Ifosfamide + Pembrolizumab Carboplatin Etoposide Ifosfamide Pembrolizumab 0 2
Carboplatin + Etoposide + Ifosfamide + Pembrolizumab + Rituximab Carboplatin Etoposide Ifosfamide Pembrolizumab Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide + Polatuzumab vedotin-piiq + Rituximab Carboplatin Etoposide Ifosfamide Polatuzumab vedotin-piiq Rituximab 0 2
Carboplatin + Etoposide + Ifosfamide + Rituximab Carboplatin Etoposide Ifosfamide Rituximab 0 7
Carboplatin + Etoposide + Ifosfamide + Rituximab + Venetoclax Carboplatin Etoposide Ifosfamide Rituximab Venetoclax 0 1
Crizotinib + Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Etoposide + Ifosfamide + Methotrexate Crizotinib Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Ifosfamide Methotrexate 1 0
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Etoposide + Hydrocortisone + Ifosfamide + Methotrexate + Prednisone + Rituximab + Vincristine Sulfate + Vindesine Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Hydrocortisone Ifosfamide Methotrexate Prednisone Rituximab Vincristine Sulfate Vindesine 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Etoposide + Ifosfamide + Methotrexate + Prednisolone + Rituximab + Vincristine Sulfate Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Ifosfamide Methotrexate Prednisolone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Etoposide + Ifosfamide + Methotrexate + Prednisolone + Vincristine Sulfate Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Ifosfamide Methotrexate Prednisolone Vincristine Sulfate 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + Etoposide + Ifosfamide + Methotrexate + Prednisolone + Rituximab Cyclophosphamide Cytarabine Dexamethasone Etoposide Ifosfamide Methotrexate Prednisolone Rituximab 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + Etoposide + Ifosfamide + Methotrexate + Prednisolone + Rituximab + Vincristine Sulfate Cyclophosphamide Cytarabine Dexamethasone Etoposide Ifosfamide Methotrexate Prednisolone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Cytarabine + Doxorubicin + Etoposide + Filgrastim + Ifosfamide + Leucovorin + Mesna + Methotrexate + Rituximab + Vincristine Sulfate Cyclophosphamide Cytarabine Doxorubicin Etoposide Filgrastim Ifosfamide Leucovorin Mesna Methotrexate Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Ganitumab + Ifosfamide + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Ganitumab Ifosfamide Vincristine Sulfate 0 0
Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Regorafenib + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Ifosfamide Regorafenib Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Ifosfamide Vincristine Sulfate 0 2
Cyclophosphamide + Etoposide + Ifosfamide + Regorafenib + Vincristine Sulfate Cyclophosphamide Etoposide Ifosfamide Regorafenib Vincristine Sulfate 0 1
Dacarbazine + Doxorubicin + Ifosfamide + Vincristine Sulfate Dacarbazine Doxorubicin Ifosfamide Vincristine Sulfate 0 1
Dactinomycin + Doxorubicin + Etoposide + Ifosfamide + Vincristine Sulfate Dactinomycin Doxorubicin Etoposide Ifosfamide Vincristine Sulfate 0 1
Dactinomycin + Doxorubicin + Ifosfamide + Vincristine Sulfate Dactinomycin Doxorubicin Ifosfamide Vincristine Sulfate 0 1
Dactinomycin + Ifosfamide + Irinotecan + Vincristine Sulfate Dactinomycin Ifosfamide Irinotecan Vincristine Sulfate 0 1
Dactinomycin + Ifosfamide + Vincristine Sulfate Dactinomycin Ifosfamide Vincristine Sulfate 0 1
Doxorubicin + Ifosfamide Doxorubicin Ifosfamide 1 5
Doxorubicin + Ifosfamide + Mesna + Olaratumab Doxorubicin Ifosfamide Mesna Olaratumab 0 1
Doxorubicin + Ifosfamide + Pazopanib Doxorubicin Ifosfamide Pazopanib 0 1
Doxorubicin + Ifosfamide + Retifanlimab Doxorubicin Ifosfamide Retifanlimab 0 1
Epirubicin + Ifosfamide + Sorafenib Epirubicin Ifosfamide Sorafenib 0 1
Etoposide + Ifosfamide Etoposide Ifosfamide 0 3
Etoposide + Ifosfamide + Lenvatinib Etoposide Ifosfamide Lenvatinib 0 1
Ifosfamide Ifosfamide 0 7
Ifosfamide + Paclitaxel Ifosfamide Paclitaxel 0 1


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