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| Drug Name | Calaspargase pegol-mknl |
| Trade Name | Asparlas |
| Synonyms | CALASP|EZN-2285EZN 2285|EZN2285|SC-PEG E. coli L-asparaginase |
| Drug Descriptions |
Asparlas (calaspargase pegol-mknl) is a pegylated version of L-asparaginase derived from E.coli, which converts L-asparagine to ammonia and L-aspartic acid, potentially resulting in reduced levels of asparagine leading to inhibition of protein synthesis and tumor cell proliferation, and increased cell death (NCI Drug Dictionary). Asparlas (calaspargase pegol-mknl) is approved as a component of multi-agent chemotherapy in acute lymphoblastic leukemia (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 941577-06-6 |
| NCIT ID | C78198 |
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