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| Drug Name | Glofitamab-gxbm |
| Trade Name | Columvi |
| Synonyms | RO 7082859|RO-7082859|RO7082859 |
| Drug Descriptions |
Columvi (glofitamab-gxbm) is a bispecific antibody that binds the tumor-associated antigen, MS4A1 (CD20), and CD3 on T-cells to stimulate T-cell killing of CD20-expressing tumor cells (PMID: 36507690). Columvi (glofitamab-gxbm) is FDA-approved for use in patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified or large B-cell lymphoma (LBCL) arising from follicular lymphoma, after two or more lines of systemic therapy (FDA.gov). |
| DrugClasses | CD20 Antibody 21 CD3 Antibody 91 |
| CAS Registry Number | 2229047-91-8 |
| NCIT ID | C148486 |
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