Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Olutasidenib
Trade Name
Synonyms FT-2102
Drug Descriptions

Olutasidenib (FT-2102) specifically targets IDH1 with mutations at amino acid R132, which results in decreased 2HG production and potentially leads to increased differentiation and decreased proliferation of IDH R132-mutant cancer cells (PMID: 31971798).

DrugClasses IDH1 Inhibitor 8
CAS Registry Number 1887014-12-1
NCIT ID C129687


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Olutasidenib Azacitidine Olutasidenib 0 2
Cisplatin + Gemcitabine + Olutasidenib Cisplatin Gemcitabine Olutasidenib 0 1
Cytarabine + Olutasidenib Cytarabine Olutasidenib 0 1
Decitabine and Cedazuridine + Olutasidenib Decitabine and Cedazuridine Olutasidenib 0 1
Nivolumab + Olutasidenib Nivolumab Olutasidenib 0 1
Olutasidenib Olutasidenib 2 2

Additional content available in CKB BOOST