Drug Detail


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Drug Name Lemzoparlimab
Trade Name
Synonyms TJC4|TJ 011133|TJ-011133|TJ011133
Drug Descriptions

Lemzoparlimab (TJ011133) is a monocloncal antibody targeting CD47, which blocks the interaction of CD47 with SIRPA to enhance macrophage mediated phagocytosis of tumor cells (Blood (2019) 134 (Supplement_1): 4063).

DrugClasses CD74 Antibody 3
CAS Registry Number 2377483-71-9
NCIT ID C163977


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Lemzoparlimab Azacitidine Lemzoparlimab 0 1
Azacitidine + Lemzoparlimab + Venetoclax Azacitidine Lemzoparlimab Venetoclax 0 1
Carfilzomib + Dexamethasone + Lemzoparlimab Carfilzomib Dexamethasone Lemzoparlimab 0 1
Daratumumab + Dexamethasone + Lemzoparlimab Daratumumab Dexamethasone Lemzoparlimab 0 1
Dexamethasone + Lemzoparlimab Dexamethasone Lemzoparlimab 0 1
Dexamethasone + Lemzoparlimab + Pomalidomide Dexamethasone Lemzoparlimab Pomalidomide 0 1
Lemzoparlimab Lemzoparlimab 0 2
Lemzoparlimab + Pembrolizumab Lemzoparlimab Pembrolizumab 0 1
Lemzoparlimab + Rituximab Lemzoparlimab Rituximab 0 1
Lemzoparlimab + Venetoclax Lemzoparlimab Venetoclax 0 0

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