Drug Detail


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Drug Name TJ011133
Trade Name
Synonyms TJC4|TJ 011133|TJ-011133|Lemzoparlimab
Drug Descriptions

TJ011133 (TJC4) is a monocloncal antibody to CD74, which blocks the interaction of CD74 with SIRPA to enhance macrophage mediated phagocytosis of tumor cells (Blood (2019) 134 (Supplement_1): 4063).

DrugClasses CD74 Antibody 3
CAS Registry Number NA
NCIT ID C163977


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + TJ011133 Azacitidine TJ011133 0 1
Azacitidine + TJ011133 + Venetoclax Azacitidine TJ011133 Venetoclax 0 1
Carfilzomib + Dexamethasone + TJ011133 Carfilzomib Dexamethasone TJ011133 0 1
Daratumumab + Dexamethasone + TJ011133 Daratumumab Dexamethasone TJ011133 0 1
Dexamethasone + Pomalidomide + TJ011133 Dexamethasone Pomalidomide TJ011133 0 1
Dexamethasone + TJ011133 Dexamethasone TJ011133 0 1
Pembrolizumab + TJ011133 Pembrolizumab TJ011133 0 1
Rituximab + TJ011133 Rituximab TJ011133 0 1
TJ011133 TJ011133 0 2

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