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Drug Name | Quizartinib |
Trade Name | |
Synonyms | Vanflyta|AC220 |
Drug Descriptions |
Vanflyta (Quizartinib) targets both wild-type and mutant FLT3 containing activating internal tandem duplications, as well as PDGFRA, RET, and KIT, which may induce apoptosis and inhibit tumor growth (PMID: 19654408, PMID: 23497317). |
DrugClasses | FLT3 Inhibitor 55 KIT Inhibitor 51 PDGFR-alpha Inhibitor 9 RET Inhibitor 39 |
CAS Registry Number | 950769-58-1 |
NCIT ID | C68936 |