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Drug Name Milademetan Tosylate
Trade Name
Synonyms DS-3032b
Drug Descriptions

Milademetan Tosylate (DS-3032b) binds to MDM2 and prevents binding to p53, resulting in activation of p53 signaling and increased tumor cell apoptosis (PMID: 29416773, PMID: 32651541).

DrugClasses MDM2 Inhibitor 20
CAS Registry Number 1398569-75-9
NCIT ID C107384

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cytarabine + Milademetan Tosylate Cytarabine Milademetan Tosylate 0 1
Cytarabine + Milademetan Tosylate + Venetoclax Cytarabine Milademetan Tosylate Venetoclax 0 1
Milademetan Tosylate Milademetan Tosylate 1 3
Milademetan Tosylate + Quizartinib Milademetan Tosylate Quizartinib 0 1


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