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Drug Name | Tremelimumab |
Trade Name | |
Synonyms | CP-675,206|Ticilimumab|CP-675206 |
Drug Descriptions |
Tremelimumab (CP-675206) binds to and inhibits cytotoxic T-lymphocyte-associated protein 4 (CTLA4), thereby enhancing T-cell activation by blocking CTLA4-mediated inhibition of T-cell activation (PMID: 32620213, PMID: 32586937). |
DrugClasses | CTLA4 Antibody 20 Immune Checkpoint Inhibitor 141 |
CAS Registry Number | 745013-59-6 |
NCIT ID | C49085 |