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Drug Name | Belinostat |
Trade Name | Beleodaq |
Synonyms | PDX101|NSC726630|PX-105684 |
Drug Descriptions |
Beleodaq (belinostat) is an HDAC inhibitor, which promotes tumor cell apoptosis, potentially leading to decreased tumor growth (PMID: 12939461, PMID: 16928830, PMID: 17935615). Beleodaq (belinostat) is FDA approved for patients with relapsed or refractory peripheral T-cell lymphoma (FDA.gov). |
DrugClasses | HDAC Inhibitor 38 |
CAS Registry Number | 414864-00-9 |
NCIT ID | C48812 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Adavosertib + Belinostat | Adavosertib Belinostat | 0 | 1 |
Atazanavir + Belinostat | Atazanavir Belinostat | 0 | 1 |
Belinostat | Belinostat | 4 | 10 |
Belinostat + Carboplatin + Paclitaxel | Belinostat Carboplatin Paclitaxel | 1 | 0 |
Belinostat + Cisplatin + Etoposide | Belinostat Cisplatin Etoposide | 0 | 1 |
Belinostat + Guadecitabine | Belinostat Guadecitabine | 0 | 1 |
Belinostat + MLN4924 | Belinostat MLN4924 | 0 | 1 |
Belinostat + Ribociclib | Belinostat Ribociclib | 0 | 1 |
Belinostat + Talazoparib | Belinostat Talazoparib | 0 | 1 |
Belinostat + Volasertib | Belinostat Volasertib | 0 | 1 |
Belinostat + Zidovudine | Belinostat Zidovudine | 0 | 1 |