Drug Detail


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Drug Name Belinostat
Trade Name Beleodaq
Synonyms PDX101|NSC726630|PX-105684
Drug Descriptions

Beleodaq (belinostat) is an HDAC inhibitor, which promotes tumor cell apoptosis, potentially leading to decreased tumor growth (PMID: 12939461, PMID: 16928830, PMID: 17935615). Beleodaq (belinostat) is FDA approved for patients with relapsed or refractory peripheral T-cell lymphoma (FDA.gov).

DrugClasses HDAC Inhibitor 45
CAS Registry Number 414864-00-9
NCIT ID C48812


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Adavosertib + Belinostat Adavosertib Belinostat 0 1
Atazanavir + Belinostat Atazanavir Belinostat 0 1
Belinostat Belinostat 2 10
Belinostat + Binimetinib Belinostat Binimetinib 0 1
Belinostat + Carboplatin + Paclitaxel Belinostat Carboplatin Paclitaxel 0 0
Belinostat + Cisplatin + Etoposide Belinostat Cisplatin Etoposide 0 2
Belinostat + Cyclophosphamide + Doxorubicin + Prednisone + Vincristine Sulfate Belinostat Cyclophosphamide Doxorubicin Prednisone Vincristine Sulfate 0 1
Belinostat + Durvalumab + Tremelimumab Belinostat Durvalumab Tremelimumab 0 1
Belinostat + Guadecitabine Belinostat Guadecitabine 0 1
Belinostat + MLN4924 Belinostat MLN4924 0 1
Belinostat + Ribociclib Belinostat Ribociclib 0 1
Belinostat + Talazoparib Belinostat Talazoparib 0 1
Belinostat + Tazemetostat Belinostat Tazemetostat 0 1
Belinostat + Volasertib Belinostat Volasertib 0 1
Belinostat + Zidovudine Belinostat Zidovudine 0 1

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