Drug Detail


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Drug Name CYC065
Trade Name
Synonyms Fadraciclib|CYC-065|CYC 065
Drug Descriptions

CYC065 (Fadraciclib) inhibits CDK2, CDK5, and CDK9, potentially resulting in decreased tumor cell growth (PMID: 28376145, PMID: 27351214, PMID: 32645016).

DrugClasses CDK2 Inhibitor 30 CDK5 Inhibitor 8 CDK9 Inhibitor 21
CAS Registry Number 1070790-89-4
NCIT ID C123902


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABT-737 + CYC065 ABT-737 CYC065 0 0
BMS986158 + CYC065 BMS986158 CYC065 0 1
CYC065 CYC065 2 3
CYC065 + Navitoclax CYC065 Navitoclax 0 0
CYC065 + Venetoclax CYC065 Venetoclax 0 1

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