Drug Detail

Drug Name Veliparib
Trade Name
Synonyms ABT-888
Drug Descriptions

Veliparib (ABT-888) is a PARP1 and PARP2 inhibitor, which inhibits DNA repair and induces lethality in homologous recombination deficient cells, and may enhance the sensitivity of chemotherapeutic agents (PMID: 26251615).

DrugClasses PARP Inhibitor (Pan) 17

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Prednisone + Veliparib Abiraterone Prednisone Veliparib 1 0
Aldoxorubicin + Cyclophosphamide + Veliparib Aldoxorubicin Cyclophosphamide Veliparib 0 1
Atezolizumab + Veliparib Atezolizumab Veliparib 0 0
AZD6482 + Veliparib AZD6482 Veliparib 1 0
B02 + Veliparib B02 Veliparib 1 0
Bendamustine + Rituximab + Veliparib Bendamustine Rituximab Veliparib 2 0
Bendamustine + Veliparib Bendamustine Veliparib 4 0
Bevacizumab + Veliparib Bevacizumab Veliparib 0 1
Capecitabine + Temozolomide + Veliparib Capecitabine Temozolomide Veliparib 0 1
Capecitabine + Veliparib Capecitabine Veliparib 0 1
Carboplatin + Dinaciclib + Veliparib Carboplatin Dinaciclib Veliparib 0 0
Carboplatin + Etoposide + Veliparib Carboplatin Etoposide Veliparib 0 4
Carboplatin + Nivolumab + Paclitaxel + Pemetrexed + Veliparib Carboplatin Nivolumab Paclitaxel Pemetrexed Veliparib 0 1
Carboplatin + Paclitaxel + Pemetrexed + Veliparib Carboplatin Paclitaxel Pemetrexed Veliparib 0 1
Carboplatin + Paclitaxel + Veliparib Carboplatin Paclitaxel Veliparib 1 1
Carboplatin + Topotecan + Veliparib Carboplatin Topotecan Veliparib 2 1
Carboplatin + Veliparib Carboplatin Veliparib 1 0
Cisplatin + Veliparib Cisplatin Veliparib 0 1
Cisplatin + Veliparib + Vinorelbine Cisplatin Veliparib Vinorelbine 1 0
Cisplatin + Veliparib + VX-970 Cisplatin VX-970 Veliparib 0 1
Cyclophosphamide + Veliparib Cyclophosphamide Veliparib 0 0
CYT01B + Veliparib CYT01B Veliparib 1 0
Dinaciclib + Veliparib Dinaciclib Veliparib 1 1
Floxuridine + Veliparib Floxuridine Veliparib 0 1
Foretinib + Veliparib Foretinib Veliparib 1 0
Irinotecan + Veliparib Irinotecan Veliparib 4 1
Lapatinib + Veliparib Lapatinib Veliparib 0 1
Mitomycin C + Veliparib Mitomycin C Veliparib 0 1
Nivolumab + Veliparib Nivolumab Veliparib 0 1
Pegylated liposomal-doxorubicin + Veliparib Pegylated liposomal-doxorubicin Veliparib 0 1
SN-38 + Veliparib SN-38 Veliparib 1 0
Temozolomide + Veliparib Temozolomide Veliparib 1 3
Topotecan + Veliparib Topotecan Veliparib 2 1
Veliparib Veliparib 8 29


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