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Drug Name AZD6482
Trade Name
Synonyms KIN-193|AZD-6482
Drug Descriptions

AZD6482 inhibits PIK3CB and PIK3CD, preventing the activation of the PI3K signaling pathway and inhibiting tumor cell proliferation, motility, and survival (PMID: 24992874, PMID: 23674493, PMID: 31292159, PMID: 30542720).

DrugClasses PIK3CB inhibitor 8 PIK3CD inhibitor 24

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Therapy Name Drugs Efficacy Evidence Clinical Trials
A66 + AZD6482 A66 AZD6482 0 0
Alpelisib + AZD6482 AZD6482 Alpelisib 0 0
Alpelisib + AZD6482 + Binimetinib AZD6482 Alpelisib Binimetinib 0 0
Alpelisib + AZD6482 + Binimetinib + Encorafenib AZD6482 Alpelisib Binimetinib Encorafenib 0 0
Alpelisib + AZD6482 + Encorafenib AZD6482 Alpelisib Encorafenib 0 0
AZD6482 AZD6482 1 0
AZD6482 + Binimetinib AZD6482 Binimetinib 0 0
AZD6482 + Binimetinib + Encorafenib AZD6482 Binimetinib Encorafenib 0 0
AZD6482 + Binimetinib + Encorafenib + NVP-AEW541 AZD6482 Binimetinib Encorafenib NVP-AEW541 0 0
AZD6482 + Binimetinib + NVP-AEW541 AZD6482 Binimetinib NVP-AEW541 0 0
AZD6482 + Encorafenib AZD6482 Encorafenib 0 0
AZD6482 + Encorafenib + NVP-AEW541 AZD6482 Encorafenib NVP-AEW541 0 0
AZD6482 + Niraparib AZD6482 Niraparib 0 0
AZD6482 + NVP-AEW541 AZD6482 NVP-AEW541 0 0
AZD6482 + Olaparib AZD6482 Olaparib 0 0
AZD6482 + Rucaparib AZD6482 Rucaparib 0 0
AZD6482 + Talazoparib AZD6482 Talazoparib 0 0
AZD6482 + Veliparib AZD6482 Veliparib 0 0


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