Drug Detail


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Drug Name AZD4573
Trade Name
Synonyms AZD-4573|AZD 4573
Drug Descriptions

AZD4573 is a selective inhibitor of Cdk9 that suppresses Mcl1 expression thus leads to apoptosis in tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr 310, PMID: 32175313, PMID: 31699827).

DrugClasses CDK9 Inhibitor 21
CAS Registry Number 2057509-72-3
NCIT ID C153377


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + AZD4573 AZD4573 Acalabrutinib 0 1
AZD4573 AZD4573 0 2
AZD4573 + Fulvestrant + Palbociclib AZD4573 Fulvestrant Palbociclib 0 0
AZD4573 + Palbociclib AZD4573 Palbociclib 0 0
AZD4573 + Venetoclax AZD4573 Venetoclax 0 0

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