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Drug Name | Debio 1347 |
Trade Name | |
Synonyms | CH5183284|FF284|debiopharm 1347 |
Drug Descriptions |
Debio 1347 inhibits FGFR-1, -2, and -3, resulting in decreased downstream signaling, and potentially leading to reduced tumor cell proliferation and angiogenesis, and increased cell death in FGFR-overexpressing tumor cells (PMID: 30745300). |
DrugClasses | FGFR1 Inhibitor 27 FGFR2 Inhibitor 22 FGFR3 Inhibitor 19 |
CAS Registry Number | 1265229-25-1 |
NCIT ID | C111988 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Debio 1347 | Debio 1347 | 55 | 2 |
Debio 1347 + Fulvestrant | Debio 1347 Fulvestrant | 0 | 1 |