Drug Detail

Drug Name Lucitanib
Trade Name
Synonyms E-3810|AL3810
Drug Descriptions

Lucitanib (E-3810) is a multi-tyrosine kinase receptor inhibitor of VEGFR 1-3, DDR2, PDGFRA, and FGFR1-2, that may inhibit tumor angiogenesis, prevent tumor cell proliferation, and induce tumor cell death (PMID: 27988457, PMID: 24696502).

DrugClasses DDR1 Inhibitor 8 DDR2 inhibitor 7 FGFR1 Inhibitor 21 FGFR2 Inhibitor 15 PDGFR-alpha Inhibitor 7 VEGFR Inhibitor (Pan) 31

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Fulvestrant + Lucitanib Abemaciclib Fulvestrant Lucitanib 0 0
Alpelisib + Lucitanib Alpelisib Lucitanib 1 0
Fulvestrant + Lucitanib Fulvestrant Lucitanib 0 0
Fulvestrant + Lucitanib + Palbociclib Fulvestrant Lucitanib Palbociclib 0 0
Lucitanib Lucitanib 6 5
Lucitanib + Rucaparib Lucitanib Rucaparib 0 1


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