Drug Detail


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Drug Name Lucitanib
Trade Name
Synonyms E-3810|AL3810
Drug Descriptions

Lucitanib (E-3810) is a multi-tyrosine kinase receptor inhibitor of VEGFR 1-3, DDR2, PDGFRA, and FGFR1-2, that may inhibit tumor angiogenesis, prevent tumor cell proliferation, and induce tumor cell death (PMID: 27988457, PMID: 24696502, PMID: 31619444).

DrugClasses DDR1 Inhibitor 8 DDR2 inhibitor 7 FGFR1 Inhibitor 26 FGFR2 Inhibitor 20 PDGFR-alpha Inhibitor 10 VEGFR Inhibitor (Pan) 33
CAS Registry Number 1058137-23-7
NCIT ID C95726


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Fulvestrant + Lucitanib Abemaciclib Fulvestrant Lucitanib 0 0
Alpelisib + Lucitanib Alpelisib Lucitanib 1 0
Fulvestrant + Lucitanib Fulvestrant Lucitanib 0 0
Fulvestrant + Lucitanib + Palbociclib Fulvestrant Lucitanib Palbociclib 0 0
Lucitanib Lucitanib 6 5
Lucitanib + Nivolumab Lucitanib Nivolumab 0 2
Lucitanib + Rucaparib Lucitanib Rucaparib 0 1

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