Drug Detail


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Drug Name Rogaratinib
Trade Name
Synonyms BAY 1163877|BAY-1163877|BAY1163877
Drug Descriptions

Rogaratinib (BAY 1163877) is a small molecule pan-FGFR inhibitor, which reduces downstream signaling, potentially resulting in decreased tumor cell proliferation (PMID: 27429073, PMID: 29451369, PMID: 30807645, PMID: 31405822).

DrugClasses FGFR Inhibitor (Pan) 23
CAS Registry Number 1443530-05-9
NCIT ID C112205


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Rogaratinib Atezolizumab Rogaratinib 0 1
Carboplatin + Paclitaxel + Rogaratinib Carboplatin Paclitaxel Rogaratinib 1 0
Copanlisib + Rogaratinib Copanlisib Rogaratinib 0 1
Crizotinib + Rogaratinib Crizotinib Rogaratinib 0 0
Docetaxel + Rogaratinib Docetaxel Rogaratinib 2 0
Fulvestrant + Palbociclib + Rogaratinib Fulvestrant Palbociclib Rogaratinib 0 1
Rogaratinib Rogaratinib 20 5

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