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Drug Name | LOXO-783 |
Trade Name | |
Synonyms | LOXO 783|LOXO783|LOX-22783|LOX 22783|LOX22783 |
Drug Descriptions |
LOXO-783 (LOX-22783) selectively inhibits PIK3CA H1047R leading to decreased downstream signaling and potentially resulting in tumor growth inhibition (Mol Cancer Ther 2021;20(12 Suppl):Abstract nr P142). |
DrugClasses | PIK3CA inhibitor 18 |
CAS Registry Number | NA |
NCIT ID | C187335 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + Anastrozole + LOXO-783 | Abemaciclib Anastrozole LOXO-783 | 0 | 1 |
Abemaciclib + Exemestane + LOXO-783 | Abemaciclib Exemestane LOXO-783 | 0 | 1 |
Abemaciclib + Fulvestrant + LOXO-783 | Abemaciclib Fulvestrant LOXO-783 | 0 | 1 |
Abemaciclib + Letrozole + LOXO-783 | Abemaciclib LOXO-783 Letrozole | 0 | 1 |
Abemaciclib + LOXO-783 + LY3484356 | Abemaciclib LOXO-783 LY3484356 | 0 | 1 |
Fulvestrant + LOXO-783 | Fulvestrant LOXO-783 | 0 | 1 |
LOXO-783 | LOXO-783 | 1 | 1 |
LOXO-783 + LY3484356 | LOXO-783 LY3484356 | 0 | 1 |
LOXO-783 + Paclitaxel | LOXO-783 Paclitaxel | 0 | 1 |