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Drug Name LY3484356
Trade Name
Synonyms LY 3484356|LY-3484356|SERD LY3484356|imlunestrant
Drug Descriptions

LY3484356 is a selective estrogen receptor degrader that binds to and causes the degradation of the estrogen receptor (ER), potentially leading to decreased ER signaling and antitumor activity (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 1050-1050).

DrugClasses Hormone - Anti-estrogens 25
CAS Registry Number NA
NCIT ID C174042


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Anastrozole + LY3484356 Abemaciclib Anastrozole LY3484356 0 1
Abemaciclib + Exemestane + LY3484356 Abemaciclib Exemestane LY3484356 0 1
Abemaciclib + Letrozole + LY3484356 Abemaciclib LY3484356 Letrozole 0 1
Abemaciclib + LOXO-783 + LY3484356 Abemaciclib LOXO-783 LY3484356 0 1
Abemaciclib + LY3484356 Abemaciclib LY3484356 0 2
Abemaciclib + LY3484356 + Trastuzumab Abemaciclib LY3484356 Trastuzumab 0 1
Alpelisib + LY3484356 Alpelisib LY3484356 0 1
Everolimus + LY3484356 Everolimus LY3484356 0 1
LOXO-783 + LY3484356 LOXO-783 LY3484356 0 1
LY3484356 LY3484356 0 4

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