Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name SDX-7320
Trade Name
Synonyms SDX7320|SDX 7320|evexomostat
Drug Descriptions

SDX-7320 is a polymer-drug conjugate of SDX-7539, an inhibitor of methionine aminopeptidase 2 (METAP2), that is attached to a polymer backbone through a cleavable linker, which potentially leads to inhibition of tumor growth (Cancer Res 2022;82(4 Suppl):Abstract nr P5-05-04).

CAS Registry Number NA
NCIT ID C128030


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + Fulvestrant + SDX-7320 Alpelisib Fulvestrant SDX-7320 0 1
Eribulin + SDX-7320 Eribulin SDX-7320 0 1
SDX-7320 SDX-7320 0 1

Additional content available in CKB BOOST