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Drug Name CFI-402257
Trade Name
Synonyms
Drug Descriptions

CFI-402257 selectively inhibits TTK (MPS1), resulting in chromosomal segregation errors, and potentially leading to decreased tumor cell growth (PMID: 28270606, PMID: 29378962).

DrugClasses MPS1 Inhibitor 27
CAS Registry Number 1610759-22-2
NCIT ID C128288

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CFI-402257 CFI-402257 0 2
CFI-402257 + Fulvestrant CFI-402257 Fulvestrant 0 1
CFI-402257 + Paclitaxel CFI-402257 Paclitaxel 0 1
CFI-402257 + unspecified PD-1 antibody CFI-402257 unspecified PD-1 antibody 0 0


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