Drug Detail

Drug Name Seribantumab
Trade Name
Synonyms MM-121|SAR256212
Drug Descriptions

Seribantumab (SAR256212) is a human monoclonal antibody that binds ERBB3 (HER3) and prevents ligand binding and heterodimerization with other ERBB family members, resulting in decreased activation of downstream signaling and potentially leading to reduced tumor growth (PMID: 26310543).

DrugClasses HER3 (ERBB3) Antibody 13

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Therapy Name Therapy Description
Exemestane + Seribantumab
Letrozole + Seribantumab
Seribantumab + XL147
Seribantumab Seribantumab (SAR256212) is a human monoclonal antibody that binds ERBB3 (HER3) and prevents ligand binding and heterodimerization with other ERBB family members, resulting in decreased activation of downstream signaling and potentially leading to reduced tumor growth (PMID: 26310543).
Fulvestrant + Seribantumab