Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name CH5132799
Trade Name
Synonyms MEN1611|CH 5132799|CH-5132799|PA 799|PA799
Drug Descriptions

MEN1611 (CH5132799) inhibits class I PI3Ks, including the PIKC3A mutants E542K, E545K, and H1047R, resulting in decreased PI3K pathway signaling and decreased tumor growth (PMID: 21558396).

DrugClasses PI3K Inhibitor (Pan) 40
CAS Registry Number 1007207-67-1
NCIT ID C158603


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + CH5132799 CH5132799 Cetuximab 0 1
CH5132799 CH5132799 14 0
CH5132799 + Everolimus CH5132799 Everolimus 0 0
CH5132799 + Fulvestrant + Trastuzumab CH5132799 Fulvestrant Trastuzumab 0 1
CH5132799 + Trastuzumab CH5132799 Trastuzumab 0 1

Additional content available in CKB BOOST