Drug Detail


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Drug Name MEN1611
Trade Name
Synonyms MEN-1611|CH 5132799|CH-5132799|PA 799|PA799|CH5132799|MEN 1611
Drug Descriptions

MEN1611 (CH5132799) inhibits class I PI3Ks, including the PIKC3A mutants E542K, E545K, and H1047R, resulting in decreased PI3K pathway signaling and decreased tumor growth (PMID: 21558396).

DrugClasses PI3K Inhibitor (Pan) 40
CAS Registry Number 1007207-67-1
NCIT ID C158603


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + MEN1611 Cetuximab MEN1611 0 1
Elacestrant + MEN1611 Elacestrant MEN1611 0 0
Eribulin + MEN1611 Eribulin MEN1611 0 1
Everolimus + MEN1611 Everolimus MEN1611 0 0
Fulvestrant + MEN1611 + Trastuzumab Fulvestrant MEN1611 Trastuzumab 0 1
Gefitinib + MEN1611 Gefitinib MEN1611 0 0
MEN1611 MEN1611 21 1
MEN1611 + Trastuzumab MEN1611 Trastuzumab 0 1

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