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Drug Name STX-478
Trade Name
Synonyms STX 478|STX478
Drug Descriptions

STX-478 inhibits PIK3CA H1047 mutations, potentially resulting in decreased tumor cell proliferation and reduced tumor growth (Cancer Res 2023;83(5 Suppl):Abstract nr P4-07-04).

DrugClasses PIK3CA inhibitor 23
CAS Registry Number NA


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fulvestrant + STX-478 Fulvestrant STX-478 0 1
Palbociclib + STX-478 Palbociclib STX-478 0 0
STX-478 STX-478 10 1

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