Drug Detail


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Drug Name Amcenestrant
Trade Name
Synonyms SAR-439859|SAR 439859|SAR439859
Drug Descriptions

Amcenestrant (SAR439859) is a selective estrogen receptor degrader that down-regulates ER expression and signaling, resulting in tumor cell growth inhibition (Cancer Res 2017;77(4 Suppl):Abstract nr P3-04-05, PMID: 31721572).

DrugClasses Hormone - Anti-estrogens 25
CAS Registry Number 2114339-57-8
NCIT ID C140354


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Amcenestrant Abemaciclib Amcenestrant 0 2
Alpelisib + Amcenestrant Alpelisib Amcenestrant 0 1
Amcenestrant Amcenestrant 0 6
Amcenestrant + Everolimus Amcenestrant Everolimus 0 1
Amcenestrant + Goserelin + Palbociclib Amcenestrant Goserelin Palbociclib 0 1
Amcenestrant + Letrozole Amcenestrant Letrozole 0 2
Amcenestrant + Midazolam Amcenestrant Midazolam 0 0
Amcenestrant + Palbociclib Amcenestrant Palbociclib 0 2

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