Drug Detail


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Drug Name Patritumab deruxtecan
Trade Name
Synonyms U3-1402|HER3-DXd|U3 1402|U31402
Drug Descriptions

Patritumab deruxtecan (U3-1402) is an antibody-drug conjugate (ADC) comprised of an ERBB3 (HER3) antibody and Exatecan, which once internalized may result in apoptotic cell death (Journal of Thoracic Oncology, 12;11S2, 2017, PMID: 31395690, PMID: 31661465, PMID: 31471314).

DrugClasses HER3 (ERBB3) Antibody 18
CAS Registry Number 2227102-46-5
NCIT ID C136987


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Osimertinib + Patritumab deruxtecan Osimertinib Patritumab deruxtecan 0 1
Patritumab deruxtecan Patritumab deruxtecan 0 9

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