Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Patritumab deruxtecan
Trade Name
Synonyms U3-1402|HER3-DXd|U3 1402|U31402
Drug Descriptions

Patritumab deruxtecan (U3-1402) is an antibody-drug conjugate (ADC) comprising an ERBB3 (HER3) antibody and Exatecan, which once internalized may result in apoptotic cell death (PMID: 31395690, PMID: 31661465, PMID: 31471314).

DrugClasses HER3 (ERBB3) Antibody 23
CAS Registry Number 2227102-46-5
NCIT ID C136987

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Letrozole + Patritumab deruxtecan Letrozole Patritumab deruxtecan 0 1
Olaparib + Patritumab deruxtecan Olaparib Patritumab deruxtecan 0 1
Osimertinib + Patritumab deruxtecan Osimertinib Patritumab deruxtecan 0 1
Patritumab deruxtecan Patritumab deruxtecan 0 14


Additional content available in CKB BOOST