Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name PF-06804103
Trade Name
Synonyms PF06804103|PF 06804103
Drug Descriptions

PF-06804103 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2)-targeting antibody linked to Aur0101, which delivers the cytotoxic drug to ERBB2 (HER2)-expressing tumor cells, potentially resulting in decreased growth of ERBB2 (HER2)-expressing tumors (Cancer Res July 1 2018 (78) (13 Supplement) 818, PMID: 32747418, PMID: 32710210).

DrugClasses HER2 (ERBB2) Antibody 73 HER2 (ERBB2) Antibody-Drug Conjugate 27
CAS Registry Number NA
NCIT ID C141420

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Letrozole + Palbociclib + PF-06804103 Letrozole PF-06804103 Palbociclib 0 1
PF-06804103 PF-06804103 0 1


Additional content available in CKB BOOST