Drug Detail

Drug Name Entrectinib
Trade Name
Synonyms RXDX-101
Drug Descriptions

Entrectinib (RXDX-101) inhibits the activity of TrkA/B/C, Ros1 fusion proteins, and Alk, which leads to induction of apoptosis and inhibition of proliferation in cells expressing these kinases (PMID: 27003761).

DrugClasses ALK Inhibitor 20 ROS1 Inhibitor 14 Trk Receptor Inhibitor (Pan) 23


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Entrectinib Entrectinib 27 7

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