Drug Detail


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Drug Name PU-H71
Trade Name
Synonyms NSC 750424|PUH71|PU H71
Drug Descriptions

PU-H71 selectively inhibits Heat shock protein 90 (Hsp90), resulting in increased proteosomal degradation of oncogenic client proteins and potentially leading to decreased tumor growth (PMID: 28808818, PMID: 32156599).

DrugClasses HSP90 Inhibitor 35
CAS Registry Number 873436-91-0
NCIT ID C101227


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Buparlisib + PU-H71 Buparlisib PU-H71 0 0
Dactolisib + PU-H71 Dactolisib PU-H71 0 0
Nab-paclitaxel + PU-H71 Nab-paclitaxel PU-H71 0 1
PU-H71 PU-H71 0 3
PU-H71 + Ruxolitinib PU-H71 Ruxolitinib 0 1

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