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Drug Name NOX66
Trade Name
Synonyms NOX 66|NOX-66
Drug Descriptions

NOX66 is a suppository formulation of idronoxil, which inhibits PI3K/Akt signaling via blockade of ENOX2, thereby potentially increasing the sensitivity of cancer cells to chemotherapeutics (PMID: 34306271).

DrugClasses
CAS Registry Number NA
NCIT ID C132257

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + NOX66 Carboplatin NOX66 0 0
Doxorubicin + NOX66 Doxorubicin NOX66 0 1
lutetium Lu 177 vipivotide tetraxetan + NOX66 NOX66 lutetium Lu 177 vipivotide tetraxetan 0 0
NOX66 NOX66 0 2


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