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Drug Name AC480
Trade Name
Synonyms BMS-599626|AC-480
Drug Descriptions

AC480 (BMS-599626) is an inhibitor of EGFR and ERBB2 (HER2), which may prevent downstream signaling and inhibit the proliferation of tumor cells that overexpress these receptors (PMID: 17062696, PMID: 21576284).

DrugClasses EGFR Inhibitor (Pan) 54 HER2 Inhibitor 33
CAS Registry Number 714971-09-2
NCIT ID C48380

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AC480 AC480 0 0
AC480 + Doxorubicin AC480 Doxorubicin 0 0
AC480 + Mitoxantrone AC480 Mitoxantrone 0 0
AC480 + Topotecan AC480 Topotecan 0 0
AC480 + Vincristine Sulfate AC480 Vincristine Sulfate 0 0


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