Drug Detail


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Drug Name Dinutuximab
Trade Name Unituxin
Synonyms MOAB Ch14.18
Drug Descriptions

Unituxin (dinutuximab) is a monoclonal antibody that targets B4GALNT1 (GD2) and increases antibody-dependent and complement-dependent cytotoxicity against GD2-expressing tumor cells (PMID: 26917818). Unituxin (dinutuximab) is FDA approved for pediatric high-risk neuroblastoma (FDA.gov).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + Dinutuximab + Etoposide + Sargramostim Cisplatin Dinutuximab Etoposide Sargramostim 0 1
Cyclophosphamide + Dinutuximab + Doxorubicin + Sargramostim + Vincristine Sulfate Cyclophosphamide Dinutuximab Doxorubicin Sargramostim Vincristine Sulfate 0 1
Dinutuximab Dinutuximab 1 2
Dinutuximab + Isotretinoin + Sargramostim Dinutuximab Isotretinoin Sargramostim 0 1

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